Steroid Resistant Nephrotic Syndrome
نویسندگان
چکیده
Minimal Change disease (MCD) is the most common cause of Nephrotic Syndrome (NS) in children accounting for 70 to 90% of cases under the age of 10 years and 50% in older children.In adults MCD is found in 10 to 15% of cases with primary nephrotic syndrome. Most patients with MCD remit with steroids.1 Remission is defined as absence of proteinuria (urine albumin nil or trace on 3 conservative days by dipstick). In children with steroid sensitive nephrotic syndrome, treatment with daily prednisolone results in remission by first 4 weeks in 95% of cases Additional 3% of children may remit after another 4 weeks of therapy. Approximately 10-20% of children suffer from steroid resistant nephrotic syndrome. (SRNS) 1
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